1 Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2 During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for (...) generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3 The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4 The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5 Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible. (shrink)

INTRODUCTION TO ASPECTS OF FACE PROCESSING: TEN QUESTIONS IN NEED OF ANSWERS. HD Ellis 1. INTRODUCTION These proceedings of the first international ...

ObjectiveTo prospectively study the cingulate cortex for the localization and role of the grasping action in humans during electrical stimulation of depth electrodes.MethodsAll the patients with intractable focal epilepsy and a depth electrode stereotactically placed in the cingulate cortex, as part of their pre-surgical epilepsy evaluation from 2015 to 2017, were included. Cortical stimulation was performed and examined for grasping actions. Post-implantation volumetric T1 MRIs were co-registered to determine the exact electrode position.ResultsFive patients exhibited contralateral grasping actions during electrical stimulation. (...) All patients had electrodes implanted in the ventral bank of the right cingulate sulcus adjacent to the vertical anterior commissure line. Stimulation of other electrodes in adjacent regions did not elicit grasping.ConclusionGrasping action elicited from a localized region in the mid-cingulate cortex directly supports the concept of the cingulate cortex being crucially involved in the grasping network. This opens an opportunity to explore this region with deep brain stimulation as a motor neuromodulation target for treatment in specific movement disorders or neurorehabilitation. (shrink)

This is the first book to offer the best essays, articles, and speeches on ethics and intelligence that demonstrate the complex moral dilemmas in intelligence collection, analysis, and operations. Some are recently declassified and never before published, and all are written by authors whose backgrounds are as varied as their insights, including Robert M. Gates, former Director of the Central Intelligence Agency; John P. Langan, the Joseph Cardinal Bernardin Professor of Catholic Social Thought at the Kennedy Institute of Ethics, Georgetown (...) University; and Loch K. Johnson, Regents Professor of Political Science at the University of Georgia and recipient of the Owens Award for contributions to the understanding of U.S. intelligence activities. Creating the foundation for the study of ethics and intelligence by filling in the gap between warfare and philosophy, this is a valuable collection of literature for building an ethical code that is not dependent on any specific agency, department, or country. (shrink)

We report on the deliberations of an interdisciplinary group of experts in science, law, and philosophy who convened to discuss novel ethical and policy challenges in stem cell research. In this report we discuss the ethical and policy implications of safety concerns in the transition from basic laboratory research to clinical applications of cell-based therapies derived from stem cells. Although many features of this transition from lab to clinic are common to other therapies, three aspects of stem cell biology pose (...) unique challenges. First, tension regarding the use of human embryos may complicate the scientific development of safe and effective cell lines. Second, because human stem cells were not developed in the laboratory until 1998, few safety questions relating to human applications have been addressed in animal research. Third, preclinical and clinical testing of biologic agents, particularly those as inherently complex as mammalian cells, present formidable challenges, such as the need to develop suitable standardized assays and the difficulty of selecting appropriate patient populations for early phase trials. We recommend that scientists, policy makers, and the public discuss these issues responsibly, and further, that a national advisory committee to oversee human trials of cell therapies be established. **NB we did not reccommend a NAC, we think it might be appropriate**. (shrink)

If stem cell-based therapies are developed, we will likely confront a difficult problem of justice: for biological reasons alone, the new therapies might benefit only a limited range of patients. In fact, they might benefit primarily white Americans, thereby exacerbating long-standing differences in health and health care.

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

This book celebrates the work of Patricia Werhane, an iconic figure in business ethics. This festschrift is a collection of articles that build on Werhane’s contributions to business ethics in such areas as Employee Rights, the Legacy of Adam Smith, Moral Imagination, Women in Business, the development of the field of business ethics, and her contributions to such fields as Health Care, Education, Teaching, and Philosophy. All papers are new contributions to the management literature written by well-known business ethicists, such (...) as Norman Bowie, Richard De George, Ronald Duska, Edwin Hartman, Michael Hoffman, Mollie Painter-Morland, Mark Schwartz, Andrew Wicks, and others. The volume is comprised of articles that reflect on Werhane’s work as well as build on it as a way to advance further research. At the end of the festschrift, Pat Werhane provides responses to each chapter. The first chapter of the book also includes the overview of Patricia Werhane’s work and her academic career. The book is written to appeal to management scholars and graduate students interested in the areas of Business Ethics, Modern Capitalism, and Human Rights. Patricia Werhane is one of the most distinguished figures in the field of business ethics. She was a founder of the field, she is one of its leading scholars, and she has had a profound impact on the world of business practice. Among her many accomplishments, Pat is known for her original work on moral imagination, she is an acclaimed authority on employee rights in the workplace, and she is one of the leading scholars on Adam Smith. Having been active in Academia for over 50 years, Werhane is a prolific author of over a hundred articles and book chapters, and the author or editor of twenty-seven books, including Adam Smith and his Legacy for Modern Capitalism, Moral Imagination and Management Decision-Making, and co-authored books Organization Ethics in Health Care, Alleviating Poverty Through Profitable Partnerships, Obstacles to Ethical Decision-Making, Corporate Responsibility: The American Experience, and Research Approaches to Business Ethics and Corporate Responsibility. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Beyond Realism & Anti-Realism: John Dewey and the NeopragmatistsAndrew W. HowatDavid L. Hildebrand Beyond Realism & Anti-Realism: John Dewey and the Neopragmatists Nashville: Vanderbilt University Press, 2003. xii + 241 pp.In this book David Hildebrand provides a spirited defence of the philosophy of John Dewey, a defence he claims is faithful to his actual views and contrary to those of the "neopragmatists," specifically Hilary Putnam and Richard Rorty. (...) Hildebrand rejects the neopragmatist assumption that Dewey's oeuvre can support one or other side of the realism/anti-realism debate, at least without obscuring some of Dewey's vital insights. In particular, he thinks Rorty and Putnam miss the centrality and significance of Dewey's "Practical Starting Point" for philosophy and his understanding of key concepts such as "knowledge," "experience" and "inquiry." He argues that when taken together these insights show that Dewey transcends traditional debates about realism, and that this was the essence of his pragmatism.The first two chapters set out Dewey's views in the context of his contemporaries (especially the New and Critical Realists). They emphasise the radical nature of Dewey's position; that it aimed to supplant the well-established philosophical dualisms and debates of the day. Chapters Three and Four recount and criticise how Rorty and Putnam employ Dewey's insights to support near-opposite ends of the realism/anti-realism debate. The final chapter summarises and recapitulates the central themes and arguments of the book.Hildebrand describes his motivating worries as "pedagogical" and "political." If contemporary pragmatists serve as authorities on the subject, [End Page 296] this threatens to occlude the significance of classical texts for new students. This would be unfortunate, as those original texts are beautiful pieces of philosophy. Moreover, there is the danger that contemporary 'authorities' on pragmatism are mistaken, or have their own distorting agenda. It is thus vital that students and professionals continue to study original texts, gaining a grasp on this subtle and rewarding era of philosophy first-hand.Hildebrand's argument is immediately plausible, given that misinterpretations and caricatures of classical pragmatism are sadly common and familiar. It is also novel however, as it asserts pragmatism's foremost contemporary representatives are also guilty of misinterpretation. Hildebrand courts controversy, concluding his introduction by saying the neopragmatists "misuse central epistemological and metaphysical views of classical pragmatism for their own ends, all the while sustaining dualisms that the classical pragmatists fought to dissolve." This book may polarise opinion about Hildebrand's success, if so contemporary debate about pragmatism should be enriched.Readers may enjoy the novel account of New and Critical Realism in Chapter One, movements of which I knew nothing before reading the book. Hildebrand uses these movements to locate Dewey historically and dialectically amid the popular realism & idealism of his time. He demonstrates Dewey's views clearly diverged from those of his contemporaries, despite some of their best efforts to assimilate them for their realist or idealist cause. His main argument concerns Dewey's view that New Realists were responsible for hypostatising the faculties of knowledge and perception and conflating their products, resulting in paradoxical psychophysical dualism. They claimed that knowledge "can be simply had, in an instant," while Dewey insisted that "knowledge is an achievement, the eventual, alembicated product of inquiry," and that contrary to the way New Realists made it sound "Knowledge is never received like manna from heaven." Dewey's work on the reflex arc illustrated that perception is similarly an active or participatory process, though its products are distinct from those of knowledge. Hildebrand argues Dewey was trying to show how such mistakes created two crippling problems for New Realism: the problem of illusion and relapse into the very idealism the movement was designed to refute.Chapter Two concerns aspects of Dewey's views which realists (New and Critical) considered at odds with their own, implying too close an affinity with idealism. Like its predecessor this chapter would benefit from more (or better) examples to help elucidate Dewey's sometimes oblique prose. The dialectic is often highly abstract, focusing on such notions as the given (versus Dewey's preferred "taken"), Dewey's unusual understanding of temporal epistemology (knowledge of past... (shrink)

Not all vertebrates share the familiar system of XX:XY sex determination seen in mammals. In the chicken and other birds, sex is determined by a ZZ:ZW sex chromosome system. Gonadal development in the chicken has provided insights into the molecular genetics of vertebrate sex determination and how it has evolved. Such comparative studies show that vertebrate sex‐determining pathways comprise both conserved and divergent elements. The chicken embryo resembles lower vertebrates in that estrogens play a central role in gonadal sex differentiation. (...) However, several genes shown to be critical for mammalian sex determination are also expressed in the chicken, but their expression patterns differ, indicating functional plasticity. While the genetic trigger for sex determination in birds remains unknown, some promising candidate genes have recently emerged. The Z‐linked gene, DMRT1, supports the Z‐dosage model of avian sex determination. Two novel W‐linked genes, ASW and FET1, represent candidate female determinants. BioEssays 26:120–132, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Sherwood Anderson's Winesburg, Ohio, published in 1919, is an episodic collection of character sketches based mostly around the perspective of George Willard, a small-town journalist who listens to the stories of various characters, often described in grotesque terms, whose passionate inner lives contrast with their limited outwardly lived existences. The initial critical response to these stories was to regard Anderson as a sort of cheap Freudian who was making an obvious criticism of American Puritanism and conformity. One reviewer, Regis Michaud, (...) wrote that Winesburg, Ohio was "entirely in keeping with the most recent contributions of American literature to psychoanalysis";1 another reviewer, H. W. Boynton. (shrink)

A review of Personhood, Ethics, and Animal Cognition: Situating Animals in Hare’s Two-Level Utilitarianism, by Gary E. Varner. New York, NY: Oxford University Press, 2012. Pp. xv + 336. H/b £40.23. and The Philosophy of Animal Minds, edited by Robert W. Lurz. New York, NY: Cambridge University Press, 2009. Pp. 320. P/b £20.21.

The only collection of Mead's writings published during his lifetime, these essays have heretofore been virtually inaccessible. Reck has collected twenty-five essays representing the full range and depth of Mead's thought. This penetrating volume will be of interest to those in philosophy, sociology, and social psychology. "The editor's well-organized introduction supplies an excellent outline of this system in its development. In view of the scattered sources from which these writings are gathered, it is a great service that this volume renders (...) not only to students of Mead, but to historians."—H. W. Schneider, _Journal of the History of Philosophy_. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...) preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Events and intellectual fashion have conspired to bring the once neglected topics of nationalism and Staatslehre to the forefront of political-philosophical debate in this country, a development which makes David Runciman’s intellectual-historical study quite timely. The history Runciman tells is that of the early twentieth century English movement of political pluralism, whose central figures were Frederic W. Maitland, John N. Figgis, Ernest Barker, George D. H. Cole, and Harold Laski. To tell their story Runciman quite properly recognizes that he must (...) also discuss Thomas Hobbes and Otto von Gierke. For the story of political pluralism is the story of a debate over the concept of group personality, the problems of which are originally and decisively formulated by Hobbes, but which are received by the English pluralists by way of Gierke. Runciman’s approach here is “somewhat dialectical”, in that the discussions of Hobbes and Gierke are meant to shed light upon the English pluralists even as the discussions of the latter are intended to illuminate them. Runciman characterizes this as a movement between philosophy and history. (shrink)

This book presents an alternative to conventional ideas about the evolution of the human intellect.

Scrutiny (1932-1953) was one of the most important critical reviews of the last century. Its editors and contributors included F. R. Leavis, Q. D. Leavis, Denys Thompson, L. C. Knights, D. W. Harding, W. H. Mellers, H. A. Mason, among others. In recasting Scrutiny’s critique of mass culture by way of Alisdair MacIntyre’s After Virtue (1981), I hope to show that the Scrutiny project not only dramatizes the conflicts internal to what MacIntyre calls emotivist culture, but provides a new way (...) of looking at the group’s relation to the culture industry, its purported elitism, and its deep ties with a communitarian rather than socialist politics. (shrink)

In Act 1 scene iv of Macbeth, Duncan reflects that: 'There's no art to find the mind's construction in the face'. In contrast, the claim that Andy Young sets out in this book is that we are now developing a science of face perception which can indeed shed light on certain aspects of mental life. Face and Mind consists of a series of seminal research and review papers on face perception published by the author and his colleagues over the last (...) 12 years. A comprehensive introductory chapter, written especially for this volume, serves to draw together the various themes explored in the different contributions. The book examines the question of how faces are special, in terms of their social, biological, and theoretical roles. In particular, Face and Mind seeks to determine what our understanding of the face can tell us about the human brain. It discusses the evidence for an evolved neural substrate for face perception, and the question of whether we are innately predisposed to recognise faces, to find them attractive, and to decode the many social signals they give us. The ability of the human brain to process and remember the many different faces that we see and subsequently recall is analysed. Young includes detailed studies of the types of impairment to face perception which can follow brain injury or psychiatric illness, and uses them to address these questions, as well as other issues of high intrinsic and interdisciplinary interest. These include the extent to which our mental lives result from the operation of discrete components devoted to different purposes, the differences between conscious and non-conscious processes, and how we use evidence to support our beliefs about the world. Because of the huge variety of social signals read from the face, it can offer unique theoretical and philosophical insights into these questions. This fascinating book will be of interest not only to psychologists and neuropsychologists working in the field of visual perception, but to cognitive scientists generally. It provides an excellent summary of the most important theorietical and empirical work done on face perception in recent years, and as such will be of interest to advanced undergraduate and post-graduate students in psychology, philosophy, and cognitive science. (shrink)